Current SATVI news
Professor Tom Scriba has co-authored a research paper titled: "S100A8/A9 regulates CD11b expression and neutrophil recruitment during chronic tuberculosis" appearing in the Journal of Clinical Investigation.
SATVI researchers Elisa Nemes, Tom Scriba, Hadn Africa, Marcia Steyn, Helen Veldtsman and Libby Briel have co-authored a research paper titled: "Fetal public Vγ9Vδ2 T cells expand and gain potent cytotoxic functions early after birth" appearing in the Proceedings of the National Academy of Science of the United States of America.
We are inviting applications for a Postdoctoral Fellowship in Computational Immunology to conduct research on a large project aimed at understanding the pathogenesis of subclinical TB and identifying immune correlates of protection against TB. The project is part of an international effort to discover immune correlates of protection against TB in the context of two phase 2b clinical trials of TB vaccination that demonstrated protection. Closing date 15 September 2020
Associate Professor Elisa Nemes has co-authored a paper titled "Targeting Unconventional Host Components for Vaccination-Induced Protection Against TB" appearing in the Frontiers in Immunology Journal.
Professor Mark Hatherill has co-authored a research paper titled "Immune serum-activated human macrophages coordinate with eosinophils to immobilize Ascaris suum larvae" appearing in the Parasite Immunology Journal.
SATVI researchers Eric Wekasa Bunyasi, Mark Hatherill, Humphrey Mulenga, Angelique Luabeya, Justin Shenje, Simon Mendelsohn, Elisa Nemes and Tom Scriba have published a research paper titled "Regional changes in tuberculosis disease burden among adolescents in South Africa (2005–2015)" appearing in the PLOS ONE journal.
Researchers the South African Tuberculosis Vaccine Initiative (SATVI), the Center for Global Infectious Disease Research (USA) and a large consortium of collaborators have developed a validated a new, simple blood-based test that has the potential to serve multiple functions in the fight against TB.
Scientists from UCT and Stanford Medicine University have developed a new method to compare and find commonalities within millions of T cell receptors (TCR), the receptors used by T cells to recognise pathogens.
The 2019 SATVI Annual Report is now available online.
Professor Val Mizrahi and Tom Scriba have co-authored a journal article titled "Renewing the Fight Against TB With an Old Vaccine" appearing in the Cell journal.
SATVI researchers Professor Tom Scriba, Associate Professor Elisa Nemes, Cheleka Mpande and Tim Reid have co-authored a journal article titled "Immune Phenotype and Functionality of Mtb-Specific T-Cells in HIV/TB Co-Infected Patients on Antiretroviral Treatment" appearing in the Pathogens journal.
Due to the lockdown announced by the South African President, we want to bring the following information to the attention of all participants in SATVI studies.